Salicylates are derivatives of salicylic acid that occur naturally in plants and serve as a natural immune hormone and preservative , protecting the plants against diseases , insects , fungi , and harmful bacteria . [ citation needed ] Salicylates can also be found in many medications , perfumes and preservatives. [ citation needed ] Both natural and synthetic salicylates can cause health problems in anyone when consumed in large doses, [ citation needed ] but for those who exhibit salicylate sensitivity (also known as salicylate intolerance ), even small doses of salicylate can cause adverse reactions.
Biofilms are a complex aggregation of microorganisms growing on a solid substrate. They can occur on organic (. dental plaque) or inorganic surfaces. Biofilms are characterized by structural heterogeneity, genetic diversity, complex community interactions, and an extracellular matrix of polymeric substances. This matrix protects the cells within it and increases their resistance to antimicrobials. Many antimicrobial agents have a difficult time eliminating organisms in a biofilm. Chlorhexidine has shown some ability to help inhibit adherence of microorganisms to a surface thereby preventing growth and development of biofilms. 6